I'd recommend Spiderman's 1962 - 1973 run (though no further due to this being where he stops developing as a character),
How do you keep developing after 11 years
As always thanks for the sweet post. Have you found the stuff you've read online, or do you own physical copies?
I've got around 400 comics bagged and boarded total, so I am a big fan.
To answer this question first, and then get to your first post, comics are a different beast than manga. Correct me if I'm wrong, but Manga is known for keeping the same writer and artist on the book for years and years at a time. Is that right?
Comics go through many more writers and artists. CC recommended a particular run because it featured a strong team, and that's usually when comics shine brightest. And a great team often happens by pure luck. Stan Lee/Jack Kirby is a big one, and the most legendary. Chris Claremont and John Byrne on X-Men back in the 80's is probably responsible for everything the average person knows about X-Men. So on and so on.
To address your first question, which is how to get into comics, the best thing to do is to tell me what you like. Who's the character you are most likely to stick with for reading a few books worth of stuff? Or what comic book movie do you really enjoy that you might want to read the original? Ultra violent or science fiction?
That's a lot easier that me just throwing endless titles at you. Nobody starts with X-Men #1 from 1968 and then read every issue up until modern day, for example, so it can be easy to get swamped by recommendations.